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97% Accuracy! Performance of Filamentous Fungi Identification with Zybio MALDI-TOF EXS2600 Verified by West China Hospital of Sichuan University

July 15, 2024 Zybio News

Recently, an essay published by Dr. Wu of West China Hospital of Sichuan University in BMC Microbiology (Impact Factor 4.0) demonstrates that rapid filamentous fungi identification with Zybio MALDI-TOF EXS2600 features 97.29% accuracy for genus-level identification and 92.79% accuracy for species-level identification by adopting formic acid sandwich method. Identification of filamentous fungi on Zybio MALDI-TOF EXS2600 greatly shortens culture turnaround time to 2-5 days from 5-10 days. 

West China Hospital of Sichuan University is a famous large-scale tertiary first-class hospital and is consistently ranked in the top 3 hospitals in China and the largest comprehensive hospital in the world.

Among the diverse microbial organisms in Microbiology, filamentous fungi hold a unique position both in the ecological as well as medical realms, such as aspergillus, mucor, Fusarium. In the essay, 117 samples of filamentous fungi were tested on Zybio EXS2600 using formic acid sandwich (FA-sandwich) versus dispersion method (mold extraction kit, MEK). The identification accuracy of FA-sandwich was 97.29% (at genus level) and 92.79% (at species level), and the identification accuracy of dispersion method was 96.39% (at genus level) and 91.89% (at species level). Compared with the ethanol formic acid extraction method, the dispersion method and FA sandwich method features simpler operation. In particular, the FA sandwich method can greatly simplify the clinical operation and is easy to use.

Zybio EXS2600 can test 480 samples per hour with target-in time less than 50 seconds. Based on an extensive database of over 4000 species, EXS2600 supports customized database offered by customers to meet local needs. With reliable performance and considerate design for customers, EXS2600 has been highly recognized in a variety of countries and regions in Europe, Asia, etc.

Zybio has always been committed to providing medical testing equipment of high quality and outstanding performance to healthcare industry worldwide. We are eagerly committed to improving patient diagnostics and healthcare and contributing to the improvement of healthcare conditions.